The Best Anti-Ageing Ingredients for 2025: What Really Works

Every year, the skincare world introduces new “miracle” ingredients — but few stand the test of time. As 2025 begins, one thing remains clear: effective anti-ageing skincare isn’t about trends, it’s about evidence.

At Pt78 Skin and Body, we believe in results grounded in science and nature. Whether your focus is hydration, repair, or prevention, understanding which ingredients actually work can transform how your skin looks and feels — now and in the years ahead.

Here are the most effective anti-ageing ingredients backed by clinical research and trusted by professionals worldwide, from natural botanicals to cutting-edge actives found in SkinCeuticals and Pt78 formulas.

1. Retinol — The Gold Standard of Anti-Ageing

Few ingredients are as clinically proven as Retinol, a derivative of Vitamin A known to accelerate cell turnover and stimulate collagen production. Retinol visibly reduces fine lines, wrinkles, uneven tone, and blemishes — making it an essential part of any long-term skincare routine.

For those new to retinol, start with encapsulated or low-percentage formulations to minimise irritation while still reaping benefits.

Try:

• Pt78 Refine A Skin Enhancer – Features 0.4% encapsulated Retinol for gradual release, combined with Bisabolol and Kakadu Plum to soothe and protect sensitive skin.

• SkinCeuticals Retinol 0.3 – Perfect for beginners seeking smoother texture and refined pores.

• SkinCeuticals Retinol 1.0 – A high-strength treatment for experienced users targeting deeper wrinkles and pigmentation.

Consistency is key — retinol delivers the best results when introduced gradually and paired with proper hydration.

2. Vitamin C — The Brightening Powerhouse

Vitamin C (ascorbic acid) is the ultimate antioxidant, known for brightening dull skin, fading pigmentation, and stimulating collagen synthesis. It also protects against free radicals caused by UV rays and pollution, making it a morning must-have.

Try:

• SkinCeuticals C E Ferulic – The global benchmark for Vitamin C serums, combining pure L-Ascorbic Acid with Vitamin E and Ferulic Acid.

• SkinCeuticals Phloretin CF – Ideal for oily or combination skin, this formula reduces discolouration and enhances firmness.

• Pt78 Highlight C Collagen Serum – A natural, vegan-friendly serum with Sodium Ascorbyl Phosphate and Davidson Plum for bright, radiant skin.

Vitamin C is best applied in the morning, followed by a broad-spectrum sunscreen for maximum protection.

3. Hyaluronic Acid — The Ultimate Hydrator

Hydration and youthfulness go hand in hand. Hyaluronic Acid (HA) binds water to the skin, giving it that smooth, plump appearance associated with healthy, youthful complexions. Over time, HA supports skin elasticity and barrier function.

Try:

• SkinCeuticals Hydrating B5 Serum – Combines Hyaluronic Acid with Vitamin B5 to deeply replenish and smooth the skin.

• Pt78 Brighten B Serum – A vegan alternative that balances hydration and brightness through a synergy of B5, B3, and Hyaluronic Acid.

For an extra moisture boost, layer your HA serum under a nourishing moisturiser such as SkinCeuticals Triple Lipid Restore 2:4:2 or Pt78 Moisture+ Hydrating Moisturiser.

4. Peptides — Collagen Support from Within

Peptides are amino acid chains that serve as the building blocks of collagen and elastin. By sending “repair signals” to the skin, peptides encourage firmness and elasticity while reducing sagging.

Try:

• SkinCeuticals Collagen III Amplifier Serum – A professional-grade peptide blend that visibly firms and tones skin.

• Pt78 Restore Peptide Serum – A gentle yet effective vegan formula promoting skin recovery and renewal overnight.

Peptides work especially well when combined with antioxidants and retinol in a nightly skincare routine.

5. Niacinamide — Calm, Bright, and Balanced

Niacinamide (Vitamin B3) is one of the most versatile skincare ingredients. It strengthens the skin barrier, reduces redness, refines pores, and improves overall tone — all while complementing more active ingredients like Retinol and Vitamin C.

Try:

• Pt78 Brighten B Serum – Features a 5% Niacinamide concentration, balanced with Panthenol and Hyaluronic Acid.

• SkinCeuticals Metacell Renewal B3 – A dermatologist-favourite for visibly firming and clarifying skin.

6. Antioxidants — Long-Term Defence Against Ageing

Environmental stressors — like UV rays, pollution, and stress — are responsible for up to 80% of visible ageing. Antioxidants are your best defence, neutralising free radicals and keeping your skin resilient.

Try:

• SkinCeuticals Resveratrol B E – A nighttime antioxidant powerhouse for smoother, firmer skin.

• Pt78 Spritz+ Hydrating Spray – Combines Rose Water, Kakadu Plum, and Green Tea Extract for antioxidant-rich hydration throughout the day.

7. Australian Botanicals — Nature’s Anti-Ageing Secret

Australia’s native flora offers some of the world’s most potent natural antioxidants and vitamins. Ingredients like Kakadu Plum, Quandong, and Davidson Plum are central to the Pt78 Skin and Body range — proven to brighten, protect, and repair naturally.

Kakadu Plum, for instance, contains the highest recorded Vitamin C content of any fruit on earth, while Quandong provides polyphenols and essential fatty acids to combat dryness and inflammation.

Explore the full Pt78 Skin and Body range to discover the next generation of natural, organic, and vegan skincare made in Australia.

Building an Anti-Ageing Routine That Lasts

An effective routine doesn’t need 10 steps — it just needs the right ingredients. Here’s a simplified version:

Morning:

1. Cleanse

2. Vitamin C serum

3. Hyaluronic Acid serum

4. Moisturiser

5. SPF

Evening:

1. Cleanse

2. Retinol or Peptide serum

3. Moisturiser or barrier cream

The Pt78 x SkinCeuticals Approach

At Pt78 Skin and Body, we’re proud to offer both worlds — clinical precision from SkinCeuticals and clean, conscious formulations from Pt78. Together, they create a skincare experience that’s luxurious, ethical, and effective.

Whether you’re just beginning your anti-ageing journey or refining an advanced routine, these ingredients are your roadmap to radiant, resilient skin in 2025 and beyond.

Explore our Products and discover what real results look like — naturally.