A.G.E. Interrupter Advanced Anti-Wrinkle Cream
Target visible signs of skin ageing caused by glycation and collagen depletion.
Recommended For:
• Dry skin
• Normal skin
• Combination skin
• Sensitive skin
• Ageing concerns
Key Benefits
Collagen-boosting formula with niacinamide and Proxylane™ helps improve skin firmness and reduce the look of deep wrinkles and fine lines.
Targets glycation—a leading cause of collagen and elastin degradation—helping restore skin elasticity and reduce sagging.
Smooths creases in high-expression zones like nasolabial folds and marionette lines while enhancing skin tone and radiance.
Strengthens the skin barrier and supports natural hyaluronic acid synthesis for deep hydration and resilience.
Gentle and effective: free of parabens, drying alcohols, and synthetic dyes. Dermatologically tested for mature and sensitive skin types.
Product Overview
A.G.E. Interrupter Advanced is a next-generation anti-wrinkle cream formulated to visibly reduce fine lines, improve skin firmness, and counteract the ageing effects of glycation—a natural process where excess sugars weaken collagen and elastin. This powerful anti-glycation treatment features:
12.6% Proxylane™ – A patented sugar-derived molecule that visibly improves skin density and supports moisture retention.
4.25% Wild Fruit Flavonoids – A potent antioxidant blend of blueberry and pomegranate extracts to combat oxidative stress and glycation.
0.1% Glycyrrhetinic Acid – A soothing, brightening agent that helps restore a healthy glow to dulled, aged skin.
Niacinamide + HEPES – A powerful combination that supports cellular repair, exfoliation, and tone improvement.
Clinically proven to reduce multiple signs of ageing in 12 weeks:
14% reduction in fine lines
11.5% reduction in forehead wrinkles
11% reduction in nasolabial folds
7% reduction in crow’s feet, marionette lines, and glabellar wrinkles
The Science Behind Skin Glycation
Skin glycation is a key driver of accelerated ageing. It occurs when sugar molecules bind to collagen and elastin, forming advanced glycation end-products (A.G.E.s). These structures stiffen and degrade the skin’s support network, leading to:
Fine lines and wrinkles
Loss of skin firmness
A dull, yellowish complexion
A.G.E. Interrupter Advanced directly targets this process, defending against further collagen breakdown while restoring youthful elasticity and radiance.
Glycation DOs & DON’Ts
✅ Do: Use daily SPF and antioxidant serums to protect against environmental accelerators of glycation.
✅ Do: Limit sugar and alcohol intake to reduce internal triggers.
❌ Don’t: Smoke or expose your skin to secondhand smoke, as it worsens oxidative damage and glycation.
SkinCeuticals A.G.E Interrupter Advanced Anti-Wrinkle Cream 48ml
1. Prep + Dispense
Start by cleansing with SkinCeuticals Glycolic Renewal Foaming Facial Cleanser.
Massage a thin, even layer of A.G.E. Interrupter Advanced anti-wrinkle cream into the skin.
With a pea-sized amount used daily, this cream typically lasts 1–2 months.
Note: Individual results may vary depending on frequency of use and amount applied.
2. Apply + Complete
For best results, apply twice daily.
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Morning: After SkinCeuticals C E Ferulic Vitamin C Serum, follow with SkinCeuticals Ultra Facial Defense SPF 50+ Sunscreen.
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Evening: If using a retinol product, apply A.G.E. Interrupter Advanced after the retinol step.
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